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MYP_021443
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Basic Information
Ixosin (1-12)
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
12 amino acids
C63H104N18O16S
Standard
Sequence
GLHKVMREVLGY
Physicochemical Analysis
1401.68 Da
8.60
0.85
0.59
0.0707
0.06
0.61
0.08
8.47
113.33
0.0833
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
557.55
-2.68
20.0
19.0
47.0
98.0
2.0
11.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0009867 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
PMID27622949 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27622949/
RECORD: Rec_0077523 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Candida albicans
128 μM
MIC
PMID27622949 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27622949/
RECORD: Rec_0079938 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
Human embryonic kidney HEK293 cells (3% Cell death at 128 microM
293 μM
Hemolysis
PMID27622949 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27622949/
RECORD: Rec_0145281 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
PMID27622949 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27622949/
RECORD: Rec_0158175 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Staphylococcus aureus ATCC 25923
128 μM
MIC
PMID27622949 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27622949/
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