‹ ›
MYP_021411
← PREVIOUS NEXT → BACK
Basic Information
Retrocyclin 3
Antimicrobial
Antiviral
Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition ▸ Entry inhibitor
Standard
18 amino acids
C82H154N36O19S6
Standard
Sequence
RICRCICGRRICRCICGR
Physicochemical Analysis
2140.72 Da
9.69
5.70
5.41
0.3167
0.29
0.77
-0.39
41.27
86.67
0.0000
0.00
375.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
929.42
-10.75
43.0
31.0
73.0
143.0
0.0
17.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0024562 VERIFIED: YES
Provenance & Taxonomy
Primates [Animal]
Defensin
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
Backbone-cyclized theta-defensin scaffold
Bio-Activity Profile
Antiviral Entry inhibitor
Herpes simplex virus 1 (Virus entry); ME-180
MTT assay
PaperTheta defensins protect cells from infection by herpes simplex virus by inhibiting viral adhesion and entry. | Yasin B, Wang W, Pang M, Cheshenko N, Hong T, Waring AJ, Herold BC, Wagar EA, Lehrer RI. | J Virol. 2004 | PMID:15113897 PMID15113897 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15113897/
RECORD: Rec_0059187 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
head-to-tail cyclic peptide [Cyclic]
noncanonical stereochemical modification [Modified]
Bio-Activity Profile
Antiviral
PaperActivity of alpha- and theta-defensins against primary isolates of HIV-1.
RECORD: Rec_0082015 VERIFIED: YES
Provenance & Taxonomy
Primates [Animal]
Defensin
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
Backbone-cyclized theta-defensin scaffold
Bio-Activity Profile
Antiviral Entry inhibitor
Herpes simplex virus 2 (Virus entry); ME-180
MTT assay
PaperTheta defensins protect cells from infection by herpes simplex virus by inhibiting viral adhesion and entry. | Yasin B, Wang W, Pang M, Cheshenko N, Hong T, Waring AJ, Herold BC, Wagar EA, Lehrer RI. | J Virol. 2004 | PMID:15113897 PMID15113897 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15113897/
RECORD: Rec_0283750 VERIFIED: YES
Provenance & Taxonomy
Silent gene [Animal]
33208
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PMID23148585 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23148585/
RECORD: Rec_0290876 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
PaperCAMP: Collection of sequences and structures of antimicrobial peptides PMID24265220 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24265220/
1 2 NEXT LAST
Showing 5 records on this page · Page 1 of 2