MYP_021376
Basic Information
MDN-0066
Antimicrobial
Standard
8 amino acids
C42H76N8O13
Standard
Sequence
LETLLSLI
Physicochemical Analysis
901.10 Da
4.05
-1.24
-1.44
-0.1546
1.84
0.53
0.58
8.75
243.75
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
344.78
-0.74
12.0
12.0
30.0
63.0
0.0
7.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0245154 VERIFIED: YES
Provenance & Taxonomy
Pseudomonas moraviensis [Bacterium]
Structure & Mods
head-to-tail cyclic peptide [Cyclic]
mixed L/D amino-acid peptide [Mixed]
Lipidation
Esterification
APD analysis reveals this sequence is most similar (50%) to Feleucin-BO1 L:50%. Chemical modification: C-terminal carboxylic acid forms an ester bond with the side chain Oh of T3. C10 fatty acid CHAIN to L1. In addition, E2, allo-T3, L4, L5, and S6 are D-amino acids
Bio-Activity Profile
Antimicrobial
P-aeruginosa CMCC10104
>25 μg/disc
MIC
RECORD: Rec_0299483 VERIFIED: YES
Provenance & Taxonomy
Pseudomonas moraviensis [Bacterium]
Structure & Mods
head-to-tail cyclic peptide [Cyclic]
mixed L/D amino-acid peptide [Mixed]
Lipidation
Esterification
APD analysis reveals this sequence is most similar (50%) to Feleucin-BO1 L:50%. Chemical modification: C-terminal carboxylic acid forms an ester bond with the side chain Oh of T3. C10 fatty acid CHAIN to L1. In addition, E2, allo-T3, L4, L5, and S6 are D-amino acids
Bio-Activity Profile
Antimicrobial
Staphylococcus aureus CMCC26003
2.5 μg/disc
MIC
RECORD: Rec_0324959 VERIFIED: YES
Provenance & Taxonomy
Pseudomonas moraviensis [Bacterium]
Structure & Mods
head-to-tail cyclic peptide [Cyclic]
mixed L/D amino-acid peptide [Mixed]
Lipidation
Esterification
APD analysis reveals this sequence is most similar (50%) to Feleucin-BO1 L:50%. Chemical modification: C-terminal carboxylic acid forms an ester bond with the side chain Oh of T3. C10 fatty acid CHAIN to L1. In addition, E2, allo-T3, L4, L5, and S6 are D-amino acids
Bio-Activity Profile
Antimicrobial
fungus C-albicans CMCC98001
>25 μg/disc
MIC
RECORD: Rec_0334225 VERIFIED: YES
Provenance & Taxonomy
Pseudomonas moraviensis [Bacterium]
Structure & Mods
head-to-tail cyclic peptide [Cyclic]
mixed L/D amino-acid peptide [Mixed]
Lipidation
Esterification
APD analysis reveals this sequence is most similar (50%) to Feleucin-BO1 L:50%. Chemical modification: C-terminal carboxylic acid forms an ester bond with the side chain Oh of T3. C10 fatty acid CHAIN to L1. In addition, E2, allo-T3, L4, L5, and S6 are D-amino acids
Bio-Activity Profile
Antimicrobial
B-subtilis CMCC63501
>25 μg/disc
MIC