Peptide Database

Peptide NameUnnamed

Function Ontology

Antimicrobial

Antiviral

Antiviral ▸ Anti-HIV

Antiviral ▸ Anti-Influenza virus ▸ Anti-Influenza

Antiviral ▸ Anti-Paramyxovirus ▸ Anti-HPIV cross

Antiviral ▸ Anti-Paramyxovirus ▸ Anti-HPIV ▸ Anti-HPIV3 cross

Antiviral ▸ Antiviral mechanism ▸ Viral fusion inhibition ▸ Fusion inhibitor

Standard StatusStandard

Sequence Length34 amino acids

Chemical FormulaC171H285N47O57

DescriptionStandard

        ITLNNSVALDPIDISIELNKAKSDLEESKEWIRR
    

Molecular Weight3911.37 Da

Isoelectric Point (pI)4.72

Net Charge (pH 7.0)-2.23

Net Charge (pH 7.4) -2.44

Charge Density (pH 7.0) -0.0655

GRAVY Index-0.49

Hydrophobic Moment 0.57

Boman Index-0.12

Instability Index57.27

Aliphatic Index 117.65

Aromaticity 0.0294

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1724.00

LogP -16.49

H-bond Donors 59.0

H-bond Acceptors 55.0

Rotatable Bonds 136.0

Heavy Atoms 275.0

Ring Count 3.0

Amide Bonds 36.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0054737 VERIFIED: NO

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyHIV gp41 fusion inhibitor

Tax ID32630.0

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitymixed L/D amino-acid peptide [Mixed]

Bio-Activity Profile

Function

Antiviral Anti-HIV Anti-Influenza Anti-HPIV3

TargetHuman parainfluenza virus 3

RECORD: Rec_0178678 VERIFIED: YES

Provenance & Taxonomy

OrganismHuman parainfluenza virus 3 [Virus]

FamilyVirus-derived peptide

Tax ID11216;0

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antiviral Fusion inhibitor

TargetHuman parainfluenza virus type 3 (Fusion); Vero

MethodImmunoprecipitation

PaperMethods for the inhibition of respiratory syncytial virus transmission | Dani Paul Bolognesi, Thomas James Matthews, Carl T. Wild, Shawn O'Lin Barney,Dennis Michael Lambert, Stephen Robert Petteway | Trimeris, Inc., Durham NC | Patent:US6440656 Evidence URLhttps://patents.google.com/patent/US6440656/en PatentUS6440656

RECORD: Rec_0306584 VERIFIED: NO

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antiviral

RECORD: Rec_0397385 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antiviral Antimicrobial