Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length423 amino acids

Chemical FormulaC2130H3343N533O604S15

DescriptionStandard

        MFLWCVLVLVNLVSVATGTNAGVKVRLTQKGLEYGRQIGIASIQQKLRTIKVPDISGTEKVDPIGKVQYSFTGMQIVNLGLPKSALALVPDTGVILSIGNAYINLHGNWRVKYLRIIKDSGSFDLAVSELTISTTVAVTSDDTGRPTVSMTNCAATVGSVNVKFHGGASWLYNLFSSFINKALRNALQKQVRNLGCDCPLYYTLITYRSLTFNLSGEFYNIGQHKEPPFSPTPFSLPSQDTNMLYIGVSAFTINSAGFVYNRAGALRLYITDDMIPSGSPIRLNTKTFGGFIPQIEKMYPGLMMKLLVETVKEPLMTFEPNNMTVQASSTVTAYAIQPNSTLSPLFVLNLEGSVSTHIYVTELKLAGNVTLNKIDMSLAKSYVGPFQVTSLDNIFTIVLKFAVIPKVNGKSFYYYYYYFLLAF
    

Molecular Weight46562.51 Da

Isoelectric Point (pI)9.29

Net Charge (pH 7.0)10.81

Net Charge (pH 7.4) 10.24

Charge Density (pH 7.0) 0.0256

GRAVY Index0.20

Hydrophobic Moment 0.72

Boman Index0.18

Instability Index31.41

Aliphatic Index 100.19

Aromaticity 0.1111

Extinction Coeff. Reduced 49280.00

Extinction Coeff. Oxidized 49530.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0223768 VERIFIED: NO

Provenance & Taxonomy

OrganismSinocyclocheilus anshuiensis [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria