Peptide Database

Peptide NameBactericidal permeability-increasing protein

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length67 amino acids

Chemical FormulaC345H545N85O100

DescriptionStandard

        SNIEVLRFENILSSILHFGVLPLANAKLQQGFPLPNPHKISFVNSDIEVLEGFLLISTDLKYETSSK
    

Molecular Weight7483.53 Da

Isoelectric Point (pI)5.48

Net Charge (pH 7.0)-2.35

Net Charge (pH 7.4) -2.68

Charge Density (pH 7.0) -0.0351

GRAVY Index0.16

Hydrophobic Moment 0.59

Boman Index0.17

Instability Index63.45

Aliphatic Index 119.25

Aromaticity 0.0896

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2957.36

LogP -24.48

H-bond Donors 98.0

H-bond Acceptors 100.0

Rotatable Bonds 248.0

Heavy Atoms 530.0

Ring Count 12.0

Amide Bonds 73.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0084747 VERIFIED: NO

Provenance & Taxonomy

OrganismMacaca mulatta [Animal]

Tax ID9544

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxic Non-hemolytic Non-ribosomal

TargetGram-negative bacteria

MethodQualitative functional evidence