Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length448 amino acids

Chemical FormulaC2230H3459N545O629S15

DescriptionStandard

        MLPSLLISLIFATLTGGENPAIQVILNNKGLQYGKNVGAGWIQDNLKRVTLPDISGKISIGFLGSVGYTLTGVSVKQCDFPEPSVQFQEDISGFKSSISGLSVALTGGWRTHYGLIHDGGSFDLAVFDVDVTSTAKLGEDADGHLSISSVNCSADVGDIKMRFRGGLPLMLILTAGFVYSSYSIQFHTVSFPVDPFLGIDLSLTNLPSVDASSLTLGLKGDFYQIKSHAGPPFKAGPFTLPKQPGFMMSVGFSEFTLNSASYVYFSAGLFSRLVNDSVIPPSSPFHLNTSSFGPYIPQLPKLFPDLLMSLQVYAREMPVFSLQPGLIRLGLLGSIKAFAIQPNATLTPLFKLNVDSKFSGKTWISDGLLKGSVEMDNLTLTLVSSEVGPFQVSKLAHGFDIPRMKHAQLVNTVLKVEEVCIHLSESLSLCLPLSVLHIYLMLFCFFFF
    

Molecular Weight48448.57 Da

Isoelectric Point (pI)6.19

Net Charge (pH 7.0)-3.65

Net Charge (pH 7.4) -4.53

Charge Density (pH 7.0) -0.0082

GRAVY Index0.34

Hydrophobic Moment 0.61

Boman Index0.24

Instability Index33.74

Aliphatic Index 102.43

Aromaticity 0.1071

Extinction Coeff. Reduced 32890.00

Extinction Coeff. Oxidized 33140.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0357896 VERIFIED: NO

Provenance & Taxonomy

OrganismMyripristis murdjan [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria