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MYP_021240
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Basic Information
MeuTXKbeta1
Antimicrobial
Antimicrobial ▸ Antibacterial
Antiparasitic ▸ Antimalarial
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
72 amino acids
C370H560N102O100S7
Standard
Sequence
GFREKHFQRFVKYAVPESTLRTVLQTVVHKVGKTQFGCPAYQGYCDDHCQDIEKKEGFCHGFKCKCGIPMGF
Physicochemical Analysis
8261.48 Da
8.82
4.05
3.54
0.0563
-0.46
0.77
-0.04
36.88
48.61
0.1389
4470.00
4845.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
3250.02
-29.16
117.0
115.0
273.0
579.0
17.0
76.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0019341 VERIFIED: YES
Provenance & Taxonomy
Arthropoda [Animal]
6656
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PMID11463163 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11463163/
RECORD: Rec_0031898 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
RMeuTXKbeta1
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiparasitic Antimalarial
Plasmodium berghei ANKA 2.34
20 μM
Growth inhibition; Microscopy (Giemsa staining)
PMID20045493 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20045493/
RECORD: Rec_0042370 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial
Mouse erythrocytes
10 μM
Hemolysis
Paperhttps://pubmed.ncbi.nlm.nih.gov/20045493/ PMID20045493 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20045493/
RECORD: Rec_0109181 VERIFIED: YES
Provenance & Taxonomy
Mesobuthus eupeus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antiparasitic
rodent malaria P. berghei (10-20 uM inbiting 89-99%), lower than scorpine but higher than shiva-3
PaperMeuTXKbeta1, a scorpion venom-derived two-domain potassium channel toxin-like peptide with cytolytic activity
RECORD: Rec_0127843 VERIFIED: YES
Provenance & Taxonomy
Mesobuthus eupeus [Animal]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Disulfide bond(s) reported
Bio-Activity Profile
Antimicrobial Antibacterial Hemolytic
mouse erythrocytes
PaperPubMed PMID: 20045493 PMID20045493 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20045493/
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