Peptide Database

Peptide NameInterferon alfacon-1

Function Ontology

Anticancer

Antimicrobial

Antiviral

Antiviral ▸ Anti-Hepatitis virus ▸ Anti-HCV

Immunology ▸ Immune modulation ▸ Immunomodulatory activity

Therapeutic / Biomedical activity ▸ Enzyme replacement therapy

Standard StatusStandard

Sequence Length167 amino acids

Chemical FormulaC870H1366N236O259S9

DescriptionStandard

        MCDLPQTHSLGNRRALILLAQMRRISPFSCLKDRHDFGFPQEEFDGNQFQKAQAISVLHEMIQQTFNLFSTKDSSAAWDESLLEKFYTELYQQLNDLEACVIQEVGVEETPLMNVDSILAVKKYFQRITLYLTEKKYSPCAWEVVRAEIMRSFSLSTNLQERLRRKE
    

Molecular Weight19564.16 Da

Isoelectric Point (pI)5.70

Net Charge (pH 7.0)-3.24

Net Charge (pH 7.4) -3.72

Charge Density (pH 7.0) -0.0194

GRAVY Index-0.38

Hydrophobic Moment 0.62

Boman Index-0.06

Instability Index60.39

Aliphatic Index 85.27

Aromaticity 0.1018

Extinction Coeff. Reduced 18450.00

Extinction Coeff. Oxidized 18700.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 8085.26

LogP -79.27

H-bond Donors 282.0

H-bond Acceptors 268.0

Rotatable Bonds 664.0

Heavy Atoms 1374.0

Ring Count 27.0

Amide Bonds 185.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0306897 VERIFIED: NO

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyInterferon

Tax ID9606

Structure & Mods

Configsingle-chain therapeutic peptide/protein [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Other ModsPhosphorylation

Bio-Activity Profile

Function

Antimicrobial Antiviral Anticancer Immunomodulatory Enzyme replacement

Half-Life1.3 hours in golden Syrian hamsters and 3.4 hours in rhesus monkeys.

RECORD: Rec_0311675 VERIFIED: YES