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MYP_021154
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Basic Information
Curvacin A (Bacteriocin)
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity
Standard
41 amino acids
C184H288N56O56S4
Standard
Sequence
ARSYGNGVYCNNKKCWVNRGEATQSIIGGMISGWASGLAGM
Physicochemical Analysis
4308.86 Da
9.31
2.77
2.55
0.0677
-0.19
0.34
0.10
27.63
61.95
0.0976
13980.00
14105.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1829.10
-23.11
67.0
63.0
142.0
300.0
6.0
45.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0345660 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
PaperTichaczek P.S., Nissen-Meyer J., Nes I.F., Vogel R.F., Hammes W.P.;. "Characterization of the bacteriocins curvacin A from Lactobacillus curvatus LTH1174 and sakacin P from L. sake LTH673."; Syst. Appl. Microbiol. 15:460-465(1992). Evidence URLhttps://www.uniprot.org/uniprotkb/SAKA_LACSK/entry
RECORD: Rec_0369869 VERIFIED: YES
Provenance & Taxonomy
Lactobacillus curvatus [Bacterium]
Bacteriocin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Listeria monocytogenes
Evidence URLhttps://camp.bicnirrh.res.in/seqDisp.php?id=CAMPSQ1829
RECORD: Rec_0400100 VERIFIED: YES
Provenance & Taxonomy
Lactobacillus curvatus [Bacterium]
bacteriocin class IIA/YGNGV family
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
10-15
Bio-Activity Profile
Antimicrobial bacteriocin class IIA YGNGV family Antibacterial Host defense
PaperPDB 2A2B structural record; NMR; chain A; residues 1-41
RECORD: Rec_0406923 VERIFIED: YES
Provenance & Taxonomy
Lactobacillus curvatus [Bacterium]
Bacteriocin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Brocothrix thermosphacta
Evidence URLhttps://camp.bicnirrh.res.in/seqDisp.php?id=CAMPSQ1829
RECORD: Rec_0426432 VERIFIED: YES
Provenance & Taxonomy
Lactobacillus curvatus [Bacterium]
Bacteriocin
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Disulfide bond(s) reported
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Listeria monocytogenes and ivanovvi
PaperPubMed PMID: 7694558 | PubMed PMID: 16331975 PMID7694558;16331975 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/7694558/
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