Peptide Database

Peptide NameIFN-α8

Function Ontology

Neurological / Signaling ▸ Receptor modulation ▸ Agonist

Neurological / Signaling ▸ Signaling peptide

Standard StatusStandard

Sequence Length166 amino acids

Chemical FormulaC865H1366N230O263S9

DescriptionStandard

        CDLPQTHSLGNRRALILLAQMRRISPFSCLKDRHDFEFPQEEFDDKQFQKAQAISVLHEMIQQTFNLFSTKDSSAALDETLLDEFYIELDQQLNDLESCVMQEVGVIESPLMYEDSILAVRKYFQRITLYLTEKKYSSCAWEVVRAEIMRSFSLSINLQKRLKSKE
    

Molecular Weight19484.07 Da

Isoelectric Point (pI)5.18

Net Charge (pH 7.0)-5.97

Net Charge (pH 7.4) -6.44

Charge Density (pH 7.0) -0.0360

GRAVY Index-0.35

Hydrophobic Moment 0.62

Boman Index-0.07

Instability Index68.65

Aliphatic Index 90.48

Aromaticity 0.0964

Extinction Coeff. Reduced 12950.00

Extinction Coeff. Oxidized 13200.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 8059.23

LogP -78.40

H-bond Donors 281.0

H-bond Acceptors 269.0

Rotatable Bonds 669.0

Heavy Atoms 1367.0

Ring Count 24.0

Amide Bonds 182.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0189700 VERIFIED: NO

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyGtoPdb endogenous peptide ligand

Tax ID9606

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidereported in GtoPdb PTM annotation

Other ModsPredicted disulphide bond formation between cysteine residues at positions 1 and 99, and 29 and 139

Bio-Activity Profile

Function

Receptor agonist Signaling peptide

TargetInterferon-α/β receptor (Human)