Peptide Database

Peptide NameNatriuretic peptides A

Function Ontology

Cardiovascular

Cardiovascular ▸ Vascular tone modulation ▸ Vasoactive peptide

Cardiovascular ▸ Vascular tone modulation ▸ Vasodilatory activity

Hormonal / Endocrine ▸ Hormone peptide

Regulatory peptide ▸ Biological modulation

Standard StatusStandard

Sequence Length27 amino acids

Chemical FormulaC117H193N43O38S4

DescriptionStandard

        SMRRSSDCFGSRIDRIGAQSGMGCGRF
    

Molecular Weight2938.31 Da

Isoelectric Point (pI)10.30

Net Charge (pH 7.0)2.44

Net Charge (pH 7.4) 2.21

Charge Density (pH 7.0) 0.0905

GRAVY Index-0.51

Hydrophobic Moment 0.64

Boman Index-0.23

Instability Index68.93

Aliphatic Index 32.59

Aromaticity 0.0741

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1348.26

LogP -20.38

H-bond Donors 53.0

H-bond Acceptors 45.0

Rotatable Bonds 101.0

Heavy Atoms 202.0

Ring Count 2.0

Amide Bonds 27.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0212091 VERIFIED: YES

Provenance & Taxonomy

OrganismPelophylax ridibundus [Animal]

FamilyNatriuretic peptides

Tax ID8406

Structure & Mods

Configdisulfide-constrained peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide8-24

Bio-Activity Profile

Function

Hormone Endocrine Vasoactive Vasodilator Cardiovascular Receptor modulation

Half-LifeMammalian: 1.9 hour; Yeast: >20 hour; E. coli: >10 hour