Peptide Database

Peptide NamerANF(Asn1-Arg98) [Rat atrial natriuretic factor]

Function Ontology

Natriuretic

Standard StatusStandard

Sequence Length98 amino acids

Chemical FormulaC459H730N128O152S3

DescriptionStandard

        NPVYSAVSNTDLMDFKNLLDHLEEKMPVEDEVMPPQALSEQTDEAGAALSSLSEVPPWTGEVNPSQRDGGALGRGPWDPSDRSALLKSKLRALLAGPR
    

Molecular Weight10569.67 Da

Isoelectric Point (pI)4.49

Net Charge (pH 7.0)-7.13

Net Charge (pH 7.4) -7.41

Charge Density (pH 7.0) -0.0727

GRAVY Index-0.56

Hydrophobic Moment 0.59

Boman Index-0.04

Instability Index46.59

Aliphatic Index 78.67

Aromaticity 0.0408

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4453.61

LogP -49.60

H-bond Donors 148.0

H-bond Acceptors 149.0

Rotatable Bonds 342.0

Heavy Atoms 742.0

Ring Count 17.0

Amide Bonds 104.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0087414 VERIFIED: YES

Provenance & Taxonomy

OrganismRattus norvegicus [Animal]

FamilyNatriuretic peptide

Tax ID10116

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Other ModsRadioiodinated peptide at Tyr-4

Bio-Activity Profile

Function

Natriuretic

MethodRadioimmunoassay

Half-LifeMale Sprague-Dawley rats plasma, in vivo; 3288 s