Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length78 amino acids

Chemical FormulaC395H618N110O106S10

DescriptionStandard

        MALIRKTFYFVFAVFFILVQQPSGCQAGLEFSEPFPSGRFAVCESCKLGRGKCRKECLENEKPDGSCRLNFLCCRQRM
    

Molecular Weight8924.46 Da

Isoelectric Point (pI)8.90

Net Charge (pH 7.0)4.43

Net Charge (pH 7.4) 4.08

Charge Density (pH 7.0) 0.0568

GRAVY Index-0.03

Hydrophobic Moment 0.46

Boman Index-0.02

Instability Index52.75

Aliphatic Index 65.00

Aromaticity 0.1282

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3493.51

LogP -31.96

H-bond Donors 129.0

H-bond Acceptors 121.0

Rotatable Bonds 297.0

Heavy Atoms 621.0

Ring Count 14.0

Amide Bonds 83.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0297692 VERIFIED: NO

Provenance & Taxonomy

OrganismMandrillus leucophaeus [Animal]

FamilyDefensin

Tax ID9568

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence