Peptide Database

Peptide NameUnnamed

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Metabolic

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Regulatory peptide ▸ Biological regulation

Standard StatusStandard

Sequence Length35 amino acids

Chemical FormulaC176H265N49O53S5

DescriptionStandard

        EASGSITCECCFNQCRIFELAQYCRLPDHFFSRIS
    

Molecular Weight4075.61 Da

Isoelectric Point (pI)5.53

Net Charge (pH 7.0)-1.12

Net Charge (pH 7.4) -1.42

Charge Density (pH 7.0) -0.0320

GRAVY Index0.00

Hydrophobic Moment 0.66

Boman Index0.01

Instability Index21.69

Aliphatic Index 61.43

Aromaticity 0.1429

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1740.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1658.16

LogP -17.56

H-bond Donors 63.0

H-bond Acceptors 58.0

Rotatable Bonds 131.0

Heavy Atoms 283.0

Ring Count 7.0

Amide Bonds 37.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0224682 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/

RECORD: Rec_0310987 VERIFIED: YES

Provenance & Taxonomy

OrganismAplysia californica [Animal]

FamilyInsulin

Tax ID6500

Structure & Mods

Configdisulfide-constrained peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide8-11

Bio-Activity Profile

Function

Hormone Endocrine Neuropeptide Neuromodulator Metabolic regulation Physiological regulation

Half-LifeMammalian: 1 hour; Yeast: 30 min; E. coli: >10 hour

RECORD: Rec_0320686 VERIFIED: YES

Provenance & Taxonomy

OrganismAplysia californica [Animal]

FamilyInsulin

Tax ID6500

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone Metabolic