Peptide Database

Peptide NameHepcidin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length88 amino acids

Chemical FormulaC428H666N118O120S12

DescriptionStandard

        MKAFSVAVAVVLVLACMFILESTAVPFSEVLTEEVGSIDSPVGEHQQPGGESMRLPEHFRFKRQSHLSLCRWCCNCCHNKGCGFCCKF
    

Molecular Weight9769.36 Da

Isoelectric Point (pI)6.86

Net Charge (pH 7.0)-0.22

Net Charge (pH 7.4) -0.79

Charge Density (pH 7.0) -0.0025

GRAVY Index0.24

Hydrophobic Moment 0.49

Boman Index0.12

Instability Index73.01

Aliphatic Index 75.23

Aromaticity 0.0909

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 6000.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3758.20

LogP -35.93

H-bond Donors 138.0

H-bond Acceptors 136.0

Rotatable Bonds 318.0

Heavy Atoms 678.0

Ring Count 17.0

Amide Bonds 92.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0065612 VERIFIED: NO

Provenance & Taxonomy

OrganismOncorhynchus mykiss [Animal]

FamilyHepcidin

Tax ID8022

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Non-hemolytic Non-ribosomal

MethodQualitative functional evidence