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MYP_020841
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Basic Information
Callyaerin C
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
not Standard
12 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
HXLLPPVXPLFG
Physicochemical Analysis
0.00 Da
0.00
0.00
0.00
0.00
0.00
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0239784 VERIFIED: YES
Provenance & Taxonomy
Callyspongia aerizusa [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
unspecified non-canonical residue at 2,8
Bio-Activity Profile
Cytotoxic
Human fibroblasts MRC-5
>100 μM
IC90
PMID26213786;20599387 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26213786/
RECORD: Rec_0357028 VERIFIED: YES
Provenance & Taxonomy
Callyspongia aerizusa [Animal]
Structure & Mods
cyclic/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
Amidation
X(2)= 4-Hydroxyproline; X(8)=Daa
Bio-Activity Profile
Antimicrobial Anticancer
THP-1
100 μM
IC50
PaperPubMed PMID: 26213786 PMID26213786 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26213786/
RECORD: Rec_0420162 VERIFIED: YES
Provenance & Taxonomy
Callyspongia aerizusa [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
unspecified non-canonical residue at 2,8
Bio-Activity Profile
Cytotoxic
Human fibroblasts MRC-5
>100 μM
IC50
PMID26213786;20599387 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26213786/
RECORD: Rec_0423894 VERIFIED: YES
Provenance & Taxonomy
Callyspongia aerizusa [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
unspecified non-canonical residue at 2,8
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Mycobacterium tuberculosis
40 μM
MIC90
PMID26213786;20599387 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26213786/
RECORD: Rec_0426321 VERIFIED: YES
Provenance & Taxonomy
Callyspongia aerizusa [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
unspecified non-canonical residue at 2,8
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Escherichia coli
PMID26213786;20599387 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26213786/
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