Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length456 amino acids

Chemical FormulaC2300H3638N628O649S10

DescriptionStandard

        TNPGFVVRITQAGLDYAHQQGIVILEKELAKLKLPDISGDSRVGRVGKVRYELSRLRLRDFHLPYSRITPISNVGLQVSISNAFAELDGNWRVKFLFIRDHGSFDLKVENVYIKIGLRLGSDASGKPTVSTSDCRTHISNVRVRFSGKLGWLYNLFHSVIESRFRKLLEDKVCDIVDESVHNELQAYVQTLPVTARIDAKTGIDYSLVAPPRATAQSLDADLKGEFYSLAHRSTVPFSPLPLAFPSDHDRMVYFGASSYFFNTAGIAYHKAGALVFEITEDMIPKEAGFHLDTSTFSAFIPQLEEMYPNMPMKFRLSTPTAPFLTIGPGGISLRPTVDAQAYAILPNSSLAPLFLLSLVRNVSAVVNVRSGRIVGSLDVGRIRLSLKDSAVGTFQVRMMQSLMNILTSSTLLPRLNARLDEGFPLPLPDRIQLSNILVRFYQNFLLLGADVRFQPR
    

Molecular Weight50791.96 Da

Isoelectric Point (pI)9.42

Net Charge (pH 7.0)9.29

Net Charge (pH 7.4) 8.48

Charge Density (pH 7.0) 0.0204

GRAVY Index0.02

Hydrophobic Moment 0.64

Boman Index0.07

Instability Index34.51

Aliphatic Index 100.68

Aromaticity 0.0943

Extinction Coeff. Reduced 31860.00

Extinction Coeff. Oxidized 31985.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0171046 VERIFIED: NO

Provenance & Taxonomy

OrganismGymnorhina tibicen (Australian magpie) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria