Peptide Database

Peptide NameDefensin-7 (Defensin; alpha 7)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antifungal

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length94 amino acids

Chemical FormulaC462H713N121O136S7

DescriptionStandard

        MRTLTLLSAFLLVALQAWAEPLQARADEMPAQKQPPADDQDVVIYFSGDDSSSLQVPGSTKGLICHCRVLYCLFGEHLGGTSFIHGERYPICCY
    

Molecular Weight10362.79 Da

Isoelectric Point (pI)5.07

Net Charge (pH 7.0)-4.28

Net Charge (pH 7.4) -4.74

Charge Density (pH 7.0) -0.0455

GRAVY Index0.09

Hydrophobic Moment 0.43

Boman Index0.14

Instability Index46.30

Aliphatic Index 90.32

Aromaticity 0.0957

Extinction Coeff. Reduced 11460.00

Extinction Coeff. Oxidized 11710.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4053.34

LogP -36.66

H-bond Donors 143.0

H-bond Acceptors 142.0

Rotatable Bonds 330.0

Heavy Atoms 726.0

Ring Count 19.0

Amide Bonds 99.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0164222 VERIFIED: YES

Provenance & Taxonomy

OrganismPan troglodytes [Animal]

FamilyAlpha-defensin; Defensin

Tax ID9598

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond; sites not specified

Bio-Activity Profile

Function

Antimicrobial Defensin Antifungal Non-hemolytic