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MYP_020795
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Basic Information
Phylloseptin-PBa
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
19 amino acids
C95H156N22O23S
Standard
Sequence
FFSMIPKIAGGIASLVKNL
Physicochemical Analysis
2006.45 Da
10.00
1.76
1.55
0.0925
1.11
0.54
0.45
4.00
128.42
0.1053
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
713.92
-3.82
24.0
26.0
66.0
141.0
3.0
19.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0309782 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa baltea [Animal]
Phylloseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer
U-251MG
1.8 μM
IC50
PaperPubMed PMID: 26633506 PMID26633506 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26633506/
RECORD: Rec_0310630 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa baltea [Animal]
Phylloseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
Horse erythrocytes: 1
PaperPubMed PMID: 26633506 PMID26633506 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26633506/
RECORD: Rec_0313920 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Anticancer
RECORD: Rec_0317190 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa baltea [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anticancer
Candida albicans
8 μg/mL
MIC
RECORD: Rec_0356560 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa baltea [Animal]
Phylloseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
Human erythrocytes
80 %
Hemolysis
PaperPubMed PMID: 26633506 PMID26633506 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26633506/
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