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MYP_020795
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Basic Information
Phylloseptin-PBa
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
19 amino acids
C95H156N22O23S
Standard
Sequence
FFSMIPKIAGGIASLVKNL
Physicochemical Analysis
2006.45 Da
10.00
1.76
1.55
0.0925
1.11
0.54
0.45
4.00
128.42
0.1053
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
713.92
-3.82
24.0
26.0
66.0
141.0
3.0
19.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0056477 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa baltea [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anticancer Anti-Gram-positive
Staphylococcus aureus
8 μg/mL
MIC
RECORD: Rec_0061065 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa baltea [Animal]
Phylloseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer
NCI-H460
4.3 μM
IC50
PaperPubMed PMID: 26633506 PMID26633506 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26633506/
RECORD: Rec_0072874 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa baltea [Animal]
Phylloseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
PaperPubMed PMID: 26633506 PMID26633506 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26633506/
RECORD: Rec_0103802 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa baltea [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anticancer Anti-Gram-negative
Escherichia coli
128 μg/mL
MIC
RECORD: Rec_0290262 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa baltea [Animal]
Phylloseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
PaperPubMed PMID: 26633506 PMID26633506 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26633506/
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