Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length114 amino acids

Chemical FormulaC564H898N146O169S3

DescriptionStandard

        PDLRGYEKFGLGNVKYNISKIHVTAVEFPSASISLIPGTGIKLVIENASLTVDMNWNIRTWMFKDSGRSTVYISKVFVTAIFSILLDNTGYTSISLNSCRTTSGDIDIKLNGKS
    

Molecular Weight12524.23 Da

Isoelectric Point (pI)9.17

Net Charge (pH 7.0)3.04

Net Charge (pH 7.4) 2.89

Charge Density (pH 7.0) 0.0267

GRAVY Index0.07

Hydrophobic Moment 0.48

Boman Index0.12

Instability Index18.06

Aliphatic Index 99.12

Aromaticity 0.0965

Extinction Coeff. Reduced 16960.00

Extinction Coeff. Oxidized 16960.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5082.93

LogP -52.27

H-bond Donors 182.0

H-bond Acceptors 176.0

Rotatable Bonds 417.0

Heavy Atoms 882.0

Ring Count 17.0

Amide Bonds 121.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0246597 VERIFIED: NO

Provenance & Taxonomy

OrganismHeliornis fulica [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria