Peptide Database

Peptide NameGlucagon

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Metabolic

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Regulatory peptide ▸ Biological regulation

Standard StatusStandard

Sequence Length29 amino acids

Chemical FormulaC152H225N41O49S

DescriptionStandard

        HSEGTFSSDYSKYLDSRRAKDFVQWLMST
    

Molecular Weight3442.72 Da

Isoelectric Point (pI)6.76

Net Charge (pH 7.0)-0.15

Net Charge (pH 7.4) -0.41

Charge Density (pH 7.0) -0.0052

GRAVY Index-0.91

Hydrophobic Moment 0.67

Boman Index-0.18

Instability Index74.11

Aliphatic Index 40.34

Aromaticity 0.1724

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8480.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1493.02

LogP -16.75

H-bond Donors 55.0

H-bond Acceptors 51.0

Rotatable Bonds 113.0

Heavy Atoms 243.0

Ring Count 7.0

Amide Bonds 29.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0036468 VERIFIED: YES

Provenance & Taxonomy

OrganismCallorhynchus milii [Animal]

FamilyGlucagon

Tax ID7868

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone Metabolic

RECORD: Rec_0193552 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/

RECORD: Rec_0230364 VERIFIED: YES

Provenance & Taxonomy

OrganismCallorhinchus milii [Animal]

FamilyGlucagon

Tax ID7868

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone Endocrine Metabolic regulation Physiological regulation

Half-LifeMammalian: 3.5 hour; Yeast: 10 min; E. coli: >10 hour

RECORD: Rec_0409445 VERIFIED: NO

Provenance & Taxonomy

OrganismCallorhynchus milii [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone