Peptide Database

Peptide NameBovine Beta-defensin 8

Function Ontology

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Standard StatusStandard

Sequence Length38 amino acids

Chemical FormulaC168H300N58O46S8

DescriptionStandard

        VRNPLSCCRNIGICVLIRCSGNMRQIGTCLGALVKCCR
    

Molecular Weight4125.06 Da

Isoelectric Point (pI)9.34

Net Charge (pH 7.0)5.66

Net Charge (pH 7.4) 5.35

Charge Density (pH 7.0) 0.1490

GRAVY Index0.56

Hydrophobic Moment 0.65

Boman Index0.02

Instability Index32.09

Aliphatic Index 107.63

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 375.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1699.80

LogP -20.31

H-bond Donors 68.0

H-bond Acceptors 60.0

Rotatable Bonds 139.0

Heavy Atoms 280.0

Ring Count 1.0

Amide Bonds 41.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0396965 VERIFIED: YES

Provenance & Taxonomy

OrganismBos taurus [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

-

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)