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MYP_020695
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Basic Information
Pisum sativum defensin 1 (Psd1; Plant defensin)
Antimicrobial
Antimicrobial ▸ Antifungal
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
46 amino acids
C216H329N67O68S8
Standard
Sequence
KTCEHLADTYRGVCFTNASCDDHCKNKAHLISGTCHNWKCFCTQNC
Physicochemical Analysis
5208.85 Da
7.73
1.03
0.50
0.0224
-0.55
0.55
-0.11
21.77
38.26
0.0870
6990.00
7490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
2195.80
-28.49
84.0
81.0
169.0
359.0
9.0
50.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0395950 VERIFIED: YES
Provenance & Taxonomy
Pisum sativum [Plant]
Defensin
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
Cyclization
3-46, 14-35, 20-40, 24-42
Bio-Activity Profile
Antimicrobial Antifungal
PD+: Aspergillus niger
7.4 μg/mL
MIC
PMID10860545;11697857;11812144 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10860545/
RECORD: Rec_0400735 VERIFIED: YES
Provenance & Taxonomy
Pisum sativum [Plant]
Defensin
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
Cyclization
3-46, 14-35, 20-40, 24-42
Bio-Activity Profile
Antimicrobial Antifungal
Neurospora crassa
0.04 μg/mL
MIC
PMID10860545;11697857;11812144 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10860545/
RECORD: Rec_0406475 VERIFIED: YES
Provenance & Taxonomy
Pisum sativum [Plant]
Defensin
3888
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
multiple disulfide bonds reported, sites not specified
Bio-Activity Profile
Antimicrobial Antifungal
Fusarium oxysporum (>100 μg/ml)
100 μg/mL
IC50
PaperPubMed PMID 10860545 | PubMed PMID 11812140 PMID10860545;11812140 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10860545/
RECORD: Rec_0411657 VERIFIED: YES
Provenance & Taxonomy
Pisum sativum [Plant]
Defensin
3888
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
multiple disulfide bonds reported, sites not specified
Bio-Activity Profile
Antimicrobial Antifungal
PaperPubMed PMID 25153857 PMID25153857 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25153857/
RECORD: Rec_0412928 VERIFIED: YES
Provenance & Taxonomy
Pisum sativum [Plant]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
Fusarium oxysporum
100 μg/mL
MIC
PMID10860545 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10860545/
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