Peptide Database

Peptide NameCircular bacteriocin; circularin A uberolysin family

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length96 amino acids

Chemical FormulaC433H723N113O123S3

DescriptionStandard

        MATLERHHKMLLLSMALGAASWLALGLISLPNLAGALGISTSNASTTVNLLSAYSTVSSVIAIVGAITGVGSIGAGIAATVLYLIKQKGKAAAALW
    

Molecular Weight9576.25 Da

Isoelectric Point (pI)10.00

Net Charge (pH 7.0)3.67

Net Charge (pH 7.4) 3.34

Charge Density (pH 7.0) 0.0382

GRAVY Index0.96

Hydrophobic Moment 0.43

Boman Index0.41

Instability Index19.07

Aliphatic Index 134.38

Aromaticity 0.0417

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 13980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3688.21

LogP -35.67

H-bond Donors 132.0

H-bond Acceptors 132.0

Rotatable Bonds 315.0

Heavy Atoms 672.0

Ring Count 9.0

Amide Bonds 99.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0174319 VERIFIED: NO

Provenance & Taxonomy

OrganismStreptococcus equi subsp. ruminatorum [Bacterium]

FamilyCircular bacteriocin

Structure & Mods

Confighead-to-tail cyclic bacteriocin scaffold [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Bacteriocin Non-hemolytic Non-ribosomal