Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length76 amino acids

Chemical FormulaC375H631N101O105S8

DescriptionStandard

        MKLLLLVLTVTLLLAQVTPVMKCWGKSGRCRTTCKQSEVFYILCKTEFKCCVEPKNVRVKPELPNTDGSLRSSSAV
    

Molecular Weight8491.16 Da

Isoelectric Point (pI)9.38

Net Charge (pH 7.0)6.44

Net Charge (pH 7.4) 6.12

Charge Density (pH 7.0) 0.0848

GRAVY Index0.16

Hydrophobic Moment 0.62

Boman Index0.02

Instability Index44.76

Aliphatic Index 98.55

Aromaticity 0.0526

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7365.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3324.29

LogP -30.66

H-bond Donors 123.0

H-bond Acceptors 120.0

Rotatable Bonds 285.0

Heavy Atoms 589.0

Ring Count 9.0

Amide Bonds 79.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0416068 VERIFIED: NO

Provenance & Taxonomy

OrganismPropithecus coquereli [Bacterium]

FamilyDefensin

Tax ID379532

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence