Peptide Database

Peptide NameGlycoprotein hormones alpha chain

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Regulatory peptide ▸ Biological modulation

Reproductive biology ▸ Reproductive modulation

Standard StatusStandard

Sequence Length93 amino acids

Chemical FormulaC452H713N129O139S12

DescriptionStandard

        YPNNEISRGGCDECRLKDNKFFSKPSAPIFQCVGCCFSRAYPTPLRSKKTMLVPKDITSEATCCVAREVTKLDNMKLENHTDCHCSTCYYHKS
    

Molecular Weight10563.06 Da

Isoelectric Point (pI)8.55

Net Charge (pH 7.0)3.93

Net Charge (pH 7.4) 3.40

Charge Density (pH 7.0) 0.0422

GRAVY Index-0.58

Hydrophobic Moment 0.66

Boman Index-0.15

Instability Index43.68

Aliphatic Index 50.32

Aromaticity 0.0860

Extinction Coeff. Reduced 5960.00

Extinction Coeff. Oxidized 6585.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4333.41

LogP -50.11

H-bond Donors 160.0

H-bond Acceptors 158.0

Rotatable Bonds 346.0

Heavy Atoms 732.0

Ring Count 17.0

Amide Bonds 98.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0091020 VERIFIED: YES

Provenance & Taxonomy

OrganismMuraenesox cinereus [Animal]

FamilyGlycoprotein hormones

Tax ID7946

Structure & Mods

Configlinear peptide with reported disulfide constraint [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

Disulfide11-35; 14-64; 32-83; 36-85; 63-88

Other Mods79:N-linked (GlcNAc...) asparagine

Bio-Activity Profile

Function

Hormone Endocrine Reproductive regulator Receptor modulation

Half-LifeMammalian: 2.8 hour; Yeast: 10 min; E. coli: 2 min