Peptide Database

Peptide NameIndolicidin [P3G,P7G,P10G]

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length13 amino acids

Chemical FormulaC91H119N25O14

DescriptionStandard

        ILGWKWGWWGWRR
    

Molecular Weight1787.08 Da

Isoelectric Point (pI)12.00

Net Charge (pH 7.0)2.76

Net Charge (pH 7.4) 2.55

Charge Density (pH 7.0) 0.2122

GRAVY Index-0.79

Hydrophobic Moment 0.52

Boman Index0.11

Instability Index80.63

Aliphatic Index 60.00

Aromaticity 0.3846

Extinction Coeff. Reduced 27500.00

Extinction Coeff. Oxidized 27500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 641.29

LogP 1.48

H-bond Donors 26.0

H-bond Acceptors 17.0

Rotatable Bonds 51.0

Heavy Atoms 130.0

Ring Count 10.0

Amide Bonds 12.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0167231 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyCathelicidin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hemolytic

Targethuman red blood cells

Activity100 % hemolysis at 7.8 μM

MethodHemolysis

RECORD: Rec_0195598 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyCathelicidin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

TargetMicrococcus luteus ATCC 9341

Activity0.4 μM

MethodMIC