Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length444 amino acids

Chemical FormulaC2182H3508N550O632S17

DescriptionStandard

        MFLWCVLVLVNLVSVATGTNAGVKVRLTQKGLEYGRQIGIASIQQKLRTIKVPDISGTEKVDYIVLYSIVNLGLPKSALGLVPDTGVMLSIGNAYINLHGNWRVNYLRIIKDSGSFDLAISELTISTTIAVTSDDTGRATVSMTNCAATVGSVNVKFHGGASSVSHSIYLLFQICPLVADSIADINPHLKTCTYKKIEISVVDIPVLAKVDQYAKIEYSMVGSPVISNTSIDLGLKGEFYNIGQHKEPPFSPTPFSLPSQDTDMLYIGVSAFTINSAGFVYNRAGALHLYITDDMIPSGSPIRLNTKTLGTFIPQIEKMYPGLMMKLLVQTVKEPAVVTAYTIQPNSTLSPLFVLNLEGSVSTHIYVTELKMAGNVTLNNLAKSYVGPFQVTSLDNIFTIVLKVVIIPKVNAHLQEGYPLPAIGNMQLVNSQLQVLKVSLCILM
    

Molecular Weight48103.60 Da

Isoelectric Point (pI)8.41

Net Charge (pH 7.0)3.16

Net Charge (pH 7.4) 2.37

Charge Density (pH 7.0) 0.0071

GRAVY Index0.34

Hydrophobic Moment 0.68

Boman Index0.22

Instability Index27.93

Aliphatic Index 113.85

Aromaticity 0.0743

Extinction Coeff. Reduced 37820.00

Extinction Coeff. Oxidized 38070.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0307419 VERIFIED: NO

Provenance & Taxonomy

OrganismSinocyclocheilus anshuiensis [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria