Peptide Database

Peptide NameHepcidin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length85 amino acids

Chemical FormulaC404H621N111O119S13

DescriptionStandard

        MKAFSVAFAVVVVLACMFILESTAVPFSEVRTEEVGSIDSPVGEHQQPGSESMHCRYVQASDHLSLCRWCCNCCHNKGCGFCCKF
    

Molecular Weight9353.77 Da

Isoelectric Point (pI)6.01

Net Charge (pH 7.0)-2.23

Net Charge (pH 7.4) -2.82

Charge Density (pH 7.0) -0.0263

GRAVY Index0.28

Hydrophobic Moment 0.49

Boman Index0.14

Instability Index71.97

Aliphatic Index 68.71

Aromaticity 0.0941

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7615.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3632.23

LogP -38.14

H-bond Donors 135.0

H-bond Acceptors 134.0

Rotatable Bonds 301.0

Heavy Atoms 647.0

Ring Count 16.0

Amide Bonds 89.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0360667 VERIFIED: NO

Provenance & Taxonomy

OrganismOncorhynchus tshawytscha [Animal]

FamilyHepcidin

Tax ID74940

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Non-hemolytic Non-ribosomal