Peptide Database

Peptide NameIFN-α16

Function Ontology

Neurological / Signaling ▸ Receptor modulation ▸ Agonist

Neurological / Signaling ▸ Signaling peptide

Standard StatusStandard

Sequence Length166 amino acids

Chemical FormulaC863H1336N232O252S9

DescriptionStandard

        CDLPQTHSLGNRRALILLAQMGRISHFSCLKDRYDFGFPQEVFDGNQFQKAQAISAFHEMIQQTFNLFSTKDSSAAWDETLLDKFYIELFQQLNDLEACVTQEVGVEEIALMNEDSILAVRKYFQRITLYLMGKKYSPCAWEVVRAEIMRSFSFSTNLQKGLRRKD
    

Molecular Weight19281.83 Da

Isoelectric Point (pI)5.96

Net Charge (pH 7.0)-1.99

Net Charge (pH 7.4) -2.45

Charge Density (pH 7.0) -0.0120

GRAVY Index-0.27

Hydrophobic Moment 0.72

Boman Index-0.01

Instability Index50.53

Aliphatic Index 82.89

Aromaticity 0.1205

Extinction Coeff. Reduced 18450.00

Extinction Coeff. Oxidized 18700.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7896.78

LogP -74.12

H-bond Donors 276.0

H-bond Acceptors 262.0

Rotatable Bonds 653.0

Heavy Atoms 1356.0

Ring Count 28.0

Amide Bonds 184.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0296876 VERIFIED: NO

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyGtoPdb endogenous peptide ligand

Tax ID9606

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidereported in GtoPdb PTM annotation

Other ModsPredicted disulphide bond formation between cysteine residues at positions 1 and 99, and 29 and 139

Bio-Activity Profile

Function

Receptor agonist Signaling peptide

TargetInterferon-α/β receptor (Human)