Peptide Database

Peptide NameProgonadoliberin-3

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Reproductive biology ▸ Reproductive modulation

Standard StatusStandard

Sequence Length59 amino acids

Chemical FormulaC304H475N83O84S3

DescriptionStandard

        QHWSYGWLPGGKRSVGELEATIKMMDTGGVVVLPEETSAHVSERLRPYDVILKKWMPHK
    

Molecular Weight6732.72 Da

Isoelectric Point (pI)8.32

Net Charge (pH 7.0)1.03

Net Charge (pH 7.4) 0.66

Charge Density (pH 7.0) 0.0175

GRAVY Index-0.47

Hydrophobic Moment 0.61

Boman Index0.01

Instability Index69.37

Aliphatic Index 79.15

Aromaticity 0.0847

Extinction Coeff. Reduced 19480.00

Extinction Coeff. Oxidized 19480.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2651.43

LogP -20.06

H-bond Donors 93.0

H-bond Acceptors 91.0

Rotatable Bonds 219.0

Heavy Atoms 474.0

Ring Count 15.0

Amide Bonds 59.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0089614 VERIFIED: YES

Provenance & Taxonomy

OrganismOncorhynchus mykiss [Animal]

FamilyProgonadoliberin

Tax ID8022

Structure & Mods

Configlinear peptide [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

N-TermPyroglutamate

Other Mods10:Glycine amide

Bio-Activity Profile

Function

Hormone Endocrine Reproductive regulator

Half-LifeMammalian: 0.8 hour; Yeast: 10 min; E. coli: >10 hour