Peptide Database

Peptide Nameretatrutide

Function Ontology

Hormonal / Endocrine ▸ Hormonal activity

Metabolic ▸ Glucose metabolism ▸ Antidiabetic

Neurological / Signaling ▸ Receptor modulation ▸ Agonist

Standard StatusStandard

Sequence Length39 amino acids

Chemical FormulaC187H281N43O60

DescriptionStandard

        YAQGTFTSDYSILLDKKAQAAFIEYLLEGGPSSGAPPPS
    

Molecular Weight4091.48 Da

Isoelectric Point (pI)4.32

Net Charge (pH 7.0)-2.24

Net Charge (pH 7.4) -2.45

Charge Density (pH 7.0) -0.0574

GRAVY Index-0.19

Hydrophobic Moment 0.42

Boman Index0.17

Instability Index61.45

Aliphatic Index 72.82

Aromaticity 0.1282

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4470.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1623.68

LogP -16.73

H-bond Donors 54.0

H-bond Acceptors 58.0

Rotatable Bonds 126.0

Heavy Atoms 290.0

Ring Count 9.0

Amide Bonds 40.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0053145 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

FamilyGtoPdb peptide ligand

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Receptor agonist Antidiabetic Hormonal activity

TargetGIP receptor (Human); GLP-1 receptor (Human); glucagon receptor (Human)

Activity0.064 nM

MethodEC50