‹ ›
MYP_020401
← PREVIOUS NEXT → BACK
Basic Information
peptide 11
Anticancer
Antimicrobial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
not Standard
9 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
KKXWKKWWK
Physicochemical Analysis
0.00 Da
0.00
0.00
0.00
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0272928 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
all-D amino-acid peptide [D]
None
Amidation
X=D-Bip (D-Biphenylalanine)
Bio-Activity Profile
Antimicrobial Anticancer
HL-60
6.1±3.4 μM
IC50
PaperDiscovery of a 9-mer Cationic Peptide (LTX-315) as a Potential First in Class Oncolytic Peptide. J Med Chem. 2016 Apr 14;59(7):2918-27. doi: 10.1021/acs.jmedchem.5b02025. PMID: 26982623. PMID26982623 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26982623/
RECORD: Rec_0284758 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
all-D amino-acid peptide [D]
None
Amidation
X=D-Bip (D-Biphenylalanine)
Bio-Activity Profile
Antimicrobial Anticancer
MCF-7
4.6±1.1 μM
IC50
PaperDiscovery of a 9-mer Cationic Peptide (LTX-315) as a Potential First in Class Oncolytic Peptide. J Med Chem. 2016 Apr 14;59(7):2918-27. doi: 10.1021/acs.jmedchem.5b02025. PMID: 26982623. PMID26982623 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26982623/
RECORD: Rec_0310647 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
all-D amino-acid peptide [D]
None
Amidation
X=D-Bip (D-Biphenylalanine)
Bio-Activity Profile
Antimicrobial Anticancer
HL-60/ADR
4.9±3.7 μM
IC50
PaperDiscovery of a 9-mer Cationic Peptide (LTX-315) as a Potential First in Class Oncolytic Peptide. J Med Chem. 2016 Apr 14;59(7):2918-27. doi: 10.1021/acs.jmedchem.5b02025. PMID: 26982623. PMID26982623 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26982623/
RECORD: Rec_0355830 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
noncanonical stereochemical modification [Modified]
None
Amidation
X=Dip (Diphenylalanine)
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
MRC-5
488±52 μM
IC50
PaperDiscovery of a 9-mer Cationic Peptide (LTX-315) as a Potential First in Class Oncolytic Peptide. J Med Chem. 2016 Apr 14;59(7):2918-27. doi: 10.1021/acs.jmedchem.5b02025. PMID: 26982623. PMID26982623 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26982623/
RECORD: Rec_0387097 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
all-D amino-acid peptide [D]
None
Amidation
X=D-Bip (D-Biphenylalanine)
Bio-Activity Profile
Antimicrobial Anticancer
IGROV-1/CDDP
6.6±2.7 μM
IC50
PaperDiscovery of a 9-mer Cationic Peptide (LTX-315) as a Potential First in Class Oncolytic Peptide. J Med Chem. 2016 Apr 14;59(7):2918-27. doi: 10.1021/acs.jmedchem.5b02025. PMID: 26982623. PMID26982623 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26982623/
FIRST PREV 1 ... 3 4 5 6 NEXT LAST
Showing 5 records · Page 5 of 6