Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length229 amino acids

Chemical FormulaC1150H1762N262O351S10

DescriptionStandard

        QIDDLAEVDYSLSGLPAVFQPFIDLDLKGVVFPAGNYTDSPYMPASFTIPDQSDSMLYLAFSEYFFQTSSFAYYTAGAFNMTIAEETCSYFNINTEIFGTIIPEVAKYSVTPNPVMLKLMATEIPIISLEQDSFTVEIQGSMEVLAVLPDSTTQSLFTMNIAANTSISLNVFDQKLMGSLCLNRLQFSLAHSNVGSFEVLLLENILSYILQTEVIPSANAKLSKGFPLP
    

Molecular Weight25194.49 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-17.14

Net Charge (pH 7.4) -17.48

Charge Density (pH 7.0) -0.0748

GRAVY Index0.31

Hydrophobic Moment 0.54

Boman Index0.25

Instability Index47.31

Aliphatic Index 98.38

Aromaticity 0.1179

Extinction Coeff. Reduced 14900.00

Extinction Coeff. Oxidized 15025.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0188182 VERIFIED: NO

Provenance & Taxonomy

OrganismDicrurus megarhynchus [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria