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MYP_020298
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Basic Information
TsAP-2
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Anti-biofilm ▸ Biofilm inhibition
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
17 amino acids
C84H136N18O19S
Standard
Sequence
FLGMIPGLIGGLISAFK
Physicochemical Analysis
1734.15 Da
8.75
0.76
0.55
0.0447
1.55
0.36
0.67
6.14
143.53
0.1176
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
566.38
-1.16
19.0
21.0
56.0
122.0
3.0
16.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0184622 VERIFIED: YES
Provenance & Taxonomy
Tityus serrulatus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antifungal
Candida albicans
50 μg/mL
MIC
RECORD: Rec_0186970 VERIFIED: YES
Provenance & Taxonomy
Tityus serrulatus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Antifungal Anticancer
Candida albicans
10 μM
MIC
PMID23770440 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23770440/
RECORD: Rec_0218350 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Anticancer
Evidence URLhttps://dramp.cpu-bioinfor.org/browse/All_Information.php?id=DRAMP03688
RECORD: Rec_0218365 VERIFIED: YES
Provenance & Taxonomy
Tityus serrulatus [Animal]
Defensin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anticancer Anti-Gram-positive
Staphylococcus aureus
5 μM
MIC
PMID23770440 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23770440/
RECORD: Rec_0240790 VERIFIED: YES
Provenance & Taxonomy
Tityus serrulatus [Animal]
Venom-derived cDNot Available library of the Brazilian yellow scorpion, Tityus serrulatus
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial
H-838
11.0 μM
IC50
PMID23770440 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23770440/
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