Peptide Database

Peptide NameCircular bacteriocin; circularin A uberolysin family

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length111 amino acids

Chemical FormulaC525H864N130O149S5

DescriptionStandard

        MNLTISKKEKLIVTSFMMASSIMIAFFGTVTGNIPITEIDFGSQSSFFATLLGLSHSSAAIVIDLINKGSTVLTIISMVSAVSGAGLIAAGGIAGIKYVIKKKGRDKAVAW
    

Molecular Weight11541.58 Da

Isoelectric Point (pI)9.82

Net Charge (pH 7.0)4.59

Net Charge (pH 7.4) 4.30

Charge Density (pH 7.0) 0.0413

GRAVY Index0.76

Hydrophobic Moment 0.55

Boman Index0.33

Instability Index19.16

Aliphatic Index 116.04

Aromaticity 0.0721

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 6990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4420.23

LogP -40.96

H-bond Donors 157.0

H-bond Acceptors 160.0

Rotatable Bonds 392.0

Heavy Atoms 809.0

Ring Count 11.0

Amide Bonds 114.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0054118 VERIFIED: NO

Provenance & Taxonomy

OrganismBacillus thuringiensis subsp. higo [Bacterium]

FamilyCircular bacteriocin

Structure & Mods

Configcyclic peptide topology reported [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Bacteriocin Non-hemolytic Non-ribosomal

RECORD: Rec_0214272 VERIFIED: NO