Peptide Database

Peptide NameBeta-defensin 3 (BD-3, mBD-3; Defensin, beta 3; Rodents, mammals, animals)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Standard StatusStandard

Sequence Length41 amino acids

Chemical FormulaC195H334N68O50S6

DescriptionStandard

        KKINNPVSCLRKGGRCWNRCIGNTRQIGSCGVPFLKCCKRK
    

Molecular Weight4623.55 Da

Isoelectric Point (pI)10.35

Net Charge (pH 7.0)10.69

Net Charge (pH 7.4) 10.40

Charge Density (pH 7.0) 0.2608

GRAVY Index-0.60

Hydrophobic Moment 0.91

Boman Index-0.27

Instability Index62.53

Aliphatic Index 61.71

Aromaticity 0.0488

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5875.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1967.29

LogP -23.73

H-bond Donors 76.0

H-bond Acceptors 67.0

Rotatable Bonds 159.0

Heavy Atoms 319.0

Ring Count 5.0

Amide Bonds 45.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0277852 VERIFIED: YES

Provenance & Taxonomy

OrganismMus musculus [Animal]

FamilyDefensin

Tax ID10090

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Disulfide9-37; 17-30; 20-38

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-negative

TargetPseudomonas aeruginosa

RECORD: Rec_0402155 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]