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MYP_020272
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Basic Information
Hainanenin 1
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
21 amino acids
C103H180N26O25S3
Standard
Sequence
FALGAVTKLLPSLLCMITRKC
Physicochemical Analysis
2278.89 Da
9.50
2.74
2.50
0.1304
1.17
0.54
0.30
31.26
134.76
0.0476
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
811.16
-4.67
31.0
31.0
75.0
157.0
2.0
20.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0379858 VERIFIED: YES
Provenance & Taxonomy
Amolops hainanensis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
15-21
Bio-Activity Profile
Antimicrobial Antifungal
Staphylococcus aureus 1349+ IS
37.5 μg/mL
MIC
PaperHainanenins: A novel family of antimicrobial peptides with strong activity from Hainan cascade-frog, Amolops hainanensis
RECORD: Rec_0391837 VERIFIED: YES
Provenance & Taxonomy
Amolops hainanensis [Animal]
Brevinin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Slime mould 090413
4.7 μg/mL
MIC
PMID22306820 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22306820/
RECORD: Rec_0398702 VERIFIED: YES
Provenance & Taxonomy
Amolops hainanensis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Staphylococcus aureus
75 μg/mL
MIC
RECORD: Rec_0407192 VERIFIED: YES
Provenance & Taxonomy
Amolops hainanensis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
15-21
Bio-Activity Profile
Antimicrobial Antifungal
C. glabrata 0902 IS
75 μg/mL
MIC
PaperHainanenins: A novel family of antimicrobial peptides with strong activity from Hainan cascade-frog, Amolops hainanensis
RECORD: Rec_0412611 VERIFIED: YES
Provenance & Taxonomy
Amolops hainanensis [Animal]
Hainanensisin
Structure & Mods
Linear peptide with a single intramolecular disulfide-stabilized loop [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
15-21
Bio-Activity Profile
Antimicrobial Antifungal
PaperS. Zhang et al. / Peptides (2012) Hainanenins: a novel family of antimicrobial peptides with strong activity from Hainan cascade-frog Amolops hainanensis. Available online 24 January 2012 Evidence URLhttps://www.uniprot.org/uniprotkb/E7EKF0/entry
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