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MYP_020272
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Basic Information
Hainanenin 1
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
21 amino acids
C103H180N26O25S3
Standard
Sequence
FALGAVTKLLPSLLCMITRKC
Physicochemical Analysis
2278.89 Da
9.50
2.74
2.50
0.1304
1.17
0.54
0.30
31.26
134.76
0.0476
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
811.16
-4.67
31.0
31.0
75.0
157.0
2.0
20.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0105638 VERIFIED: YES
Provenance & Taxonomy
Amolops hainanensis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
15-21
Bio-Activity Profile
Antimicrobial Antifungal
N. asteroides 090312 IS
18.8 μg/mL
MIC
PaperHainanenins: A novel family of antimicrobial peptides with strong activity from Hainan cascade-frog, Amolops hainanensis
RECORD: Rec_0106367 VERIFIED: YES
Provenance & Taxonomy
Amolops hainanensis [Animal]
Brevinin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus 090223
4.7 μg/mL
MIC
PMID22306820 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22306820/
RECORD: Rec_0142261 VERIFIED: YES
Provenance & Taxonomy
Amolops hainanensis [Animal]
Brevinin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Aeromonas sobria 090223
18.8 μg/mL
MIC
PMID22306820 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22306820/
RECORD: Rec_0143371 VERIFIED: YES
Provenance & Taxonomy
Amolops hainanensis [Animal]
Hainanensisin
Structure & Mods
Linear peptide with a single intramolecular disulfide-stabilized loop [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
15-21
Bio-Activity Profile
Hemolytic Cytolytic
Erythrocytes
20.0 μM
HC50
PaperS. Zhang et al. / Peptides (2012) Hainanenins: a novel family of antimicrobial peptides with strong activity from Hainan cascade-frog Amolops hainanensis. Available online 24 January 2012 Evidence URLhttps://www.uniprot.org/uniprotkb/E7EKF0/entry
RECORD: Rec_0167001 VERIFIED: YES
Provenance & Taxonomy
Amolops hainanensis [Animal]
Brevinin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Candida glabrata 0902
75 μg/mL
MIC
PMID22306820 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22306820/
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