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MYP_020257
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Basic Information
H/V-peptide (1-11)(19-25)[K4N]
Antimicrobial
Antimicrobial ▸ Antibacterial
Antiparasitic ▸ Antiprotozoal
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
18 amino acids
C88H165N27O23
Standard
Sequence
GILNTIKSIASKLKRKAK
Physicochemical Analysis
1969.42 Da
11.39
5.76
5.54
0.3197
-0.31
0.70
-0.18
14.67
119.44
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
853.80
-8.31
31.0
29.0
74.0
138.0
0.0
18.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0036639 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antiparasitic Antiprotozoal
Klebsiella pneumoniae 1625
3.12 μM
MIC
PMID23403131 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23403131/
RECORD: Rec_0042569 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antiparasitic Antiprotozoal
Pseudomonas aeruginosa 4677
50 μM
MIC
PMID23403131 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23403131/
RECORD: Rec_0062367 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antiparasitic Antiprotozoal
Escherichia coli 170
1.56 μM
MIC
PMID23403131 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23403131/
RECORD: Rec_0068234 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antiparasitic Antiprotozoal
Plasmodium berghei[40-50% Inhibition = 5 microM
PMID23403131 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23403131/
RECORD: Rec_0106459 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 66.7%, E 0.0%, T 5.6%, C 27.8% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Toxic Antimicrobial Hemolytic
PaperHemolytik: a database of experimentally determined hemolytic and non-hemolytic peptides PMID24174543 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24174543/
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