Peptide Database

Peptide NameColicin-E7 (EC 3.1.-.-)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length57 amino acids

Chemical FormulaC276H456N86O79S2

DescriptionStandard

        MSIGKAAKTRKSDAVGKRSSFEIHHVHEVAKGGDIYNVENMLILTPKRHVDIHKGAK
    

Molecular Weight6307.23 Da

Isoelectric Point (pI)9.90

Net Charge (pH 7.0)4.94

Net Charge (pH 7.4) 4.45

Charge Density (pH 7.0) 0.0866

GRAVY Index-0.55

Hydrophobic Moment 0.49

Boman Index-0.11

Instability Index49.27

Aliphatic Index 82.11

Aromaticity 0.0351

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2672.98

LogP -27.24

H-bond Donors 94.0

H-bond Acceptors 91.0

Rotatable Bonds 220.0

Heavy Atoms 443.0

Ring Count 8.0

Amide Bonds 58.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0228654 VERIFIED: NO

Provenance & Taxonomy

OrganismPseudomonas fluorescens [Bacterium]

FamilyPyocin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Bacteriocin Hydrolase Non-hemolytic Non-ribosomal