Peptide Database

Peptide NameTP1[V6R, R9A] (Derived from TP1)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antifungal

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Standard StatusStandard

Sequence Length17 amino acids

Chemical FormulaC97H150N34O20S4

DescriptionStandard

        KWCFRRCYAGICYRRCR
    

Molecular Weight2240.70 Da

Isoelectric Point (pI)9.93

Net Charge (pH 7.0)5.72

Net Charge (pH 7.4) 5.45

Charge Density (pH 7.0) 0.3363

GRAVY Index-0.66

Hydrophobic Moment 0.47

Boman Index-0.47

Instability Index75.79

Aliphatic Index 28.82

Aromaticity 0.2353

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8730.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 920.69

LogP -7.12

H-bond Donors 41.0

H-bond Acceptors 30.0

Rotatable Bonds 71.0

Heavy Atoms 155.0

Ring Count 5.0

Amide Bonds 16.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0374959 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative

TargetAcinetobacter baumannii BAA

Activity16 μg/mL

MethodMIC

RECORD: Rec_0399106 VERIFIED: YES

Provenance & Taxonomy

OrganismSynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configstapled cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermAmidation

Disulfide3-16; 7-12

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal

TargetBacillus subtilis ATCC 6051

Activity0.25 μg/mL

MethodMIC

RECORD: Rec_0402246 VERIFIED: YES

Provenance & Taxonomy

OrganismSynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configstapled cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermAmidation

Disulfide3-16; 7-12

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal Cytotoxic

Targetcells, unspecified

Activity100 μg/mL

MethodCytotoxicity assay

RECORD: Rec_0421609 VERIFIED: YES

Provenance & Taxonomy

OrganismSynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configstapled cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermAmidation

Disulfide3-16; 7-12

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal

TargetCandida albicans ATCC 90028

Activity16 μg/mL

MethodMIC

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