Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length76 amino acids

Chemical FormulaC379H629N107O105S7

DescriptionStandard

        MKRILLVLTVSLLLAQVTQARHCWKKLGRCRTTCKDSEVFYLLCSDETKCCVNPKHVPVKTRSLPPTGSLETSAVW
    

Molecular Weight8589.16 Da

Isoelectric Point (pI)9.42

Net Charge (pH 7.0)6.62

Net Charge (pH 7.4) 6.20

Charge Density (pH 7.0) 0.0871

GRAVY Index0.00

Hydrophobic Moment 0.73

Boman Index-0.02

Instability Index40.53

Aliphatic Index 96.05

Aromaticity 0.0526

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3410.46

LogP -32.02

H-bond Donors 128.0

H-bond Acceptors 121.0

Rotatable Bonds 283.0

Heavy Atoms 598.0

Ring Count 12.0

Amide Bonds 78.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0077104 VERIFIED: NO

Provenance & Taxonomy

OrganismFelis catus [Animal]

FamilyDefensin

Tax ID9685

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence