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MYP_020181
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Basic Information
saBD
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Immunology ▸ Immune cell migration ▸ Chemotactic peptide
Standard
42 amino acids
C205H308N50O51S5
Standard
Sequence
ASFPWSCPSLSGVCRKVCLPTELFFGPLGCGKGFLCGVSHFL
Physicochemical Analysis
4449.27 Da
8.44
1.83
1.52
0.0437
0.72
0.48
0.34
35.82
78.81
0.1429
5500.00
5750.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1538.35
-12.37
58.0
59.0
134.0
311.0
12.0
41.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0000412 VERIFIED: NO
Provenance & Taxonomy
Actinopterygii [Animal]
7898
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
RECORD: Rec_0060032 VERIFIED: YES
Provenance & Taxonomy
Sparus aurata [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Vibrio anguillarum
PaperMolecular and functional characterization of the gilthead seabream ?-defensin demonstrate its chemotactic and antimicrobial activity
RECORD: Rec_0083280 VERIFIED: YES
Provenance & Taxonomy
Collichthys lucidus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0129082 VERIFIED: YES
Provenance & Taxonomy
Sparus aurata [Animal]
Defensin
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Bacillus subtilis (strong activity)
PaperPubMed PMID: 21497909 PMID21497909 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21497909/
RECORD: Rec_0131507 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 7.1%, E 14.3%, T 45.2%, C 33.3% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antibacterial Antimicrobial Anti-Gram-positive Anti-Gram-negative Chemotactic
PaperAPD2: the updated antimicrobial peptide database and its application in peptide design PMID18957441 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18957441/
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