Peptide Database

Peptide NameColicin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length189 amino acids

Chemical FormulaC906H1443N267O284S

DescriptionStandard

        VPASIPVVDAKPTTHPGVFSVSVPGLPDLQVSTVKNAPAMTALPRGVTDEKDRTVHPAGFTFGGSSHEAVIRFPKESGQAPVYVSVTDVLTPEQVKQRQDEENRRQQEWDATHPVEVAERNYRLASDELNRANVDVAGKQERQIQAAHAVAARKGELDAANKTFADAKEEIKKFERFAHDPAILQKAIT
    

Molecular Weight20651.83 Da

Isoelectric Point (pI)6.10

Net Charge (pH 7.0)-2.70

Net Charge (pH 7.4) -3.27

Charge Density (pH 7.0) -0.0143

GRAVY Index-0.57

Hydrophobic Moment 0.75

Boman Index-0.09

Instability Index42.08

Aliphatic Index 74.34

Aromaticity 0.0529

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8480.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 8858.89

LogP -111.52

H-bond Donors 298.0

H-bond Acceptors 288.0

Rotatable Bonds 678.0

Heavy Atoms 1458.0

Ring Count 31.0

Amide Bonds 205.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0398177 VERIFIED: YES

Provenance & Taxonomy

OrganismSalmonella enterica [Bacterium]

Structure & Mods

Configlinear polypeptide/propeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Antibiotic Bacteriocin Non-hemolytic Non-ribosomal

TargetEscherichia coli