Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length146 amino acids

Chemical FormulaC721H1164N206O217S14

DescriptionStandard

        MQDHLKHILLEYHKTCGLSSPKKSFTMKILLFFSTFLFFGVFIPPVGSGQTVGNSDSSSKIMCRRKLETLYSEARNSSTTSENTQYGTEENKTAKRKEHTVALNRRLACTMLGGQCKNKCGEKEFRIIYCERPTTLCCMRECDSKK
    

Molecular Weight16639.12 Da

Isoelectric Point (pI)9.28

Net Charge (pH 7.0)9.78

Net Charge (pH 7.4) 9.18

Charge Density (pH 7.0) 0.0670

GRAVY Index-0.53

Hydrophobic Moment 0.64

Boman Index-0.13

Instability Index57.96

Aliphatic Index 61.44

Aromaticity 0.0822

Extinction Coeff. Reduced 5960.00

Extinction Coeff. Oxidized 6460.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6910.24

LogP -77.51

H-bond Donors 254.0

H-bond Acceptors 245.0

Rotatable Bonds 572.0

Heavy Atoms 1158.0

Ring Count 20.0

Amide Bonds 155.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0176634 VERIFIED: NO

Provenance & Taxonomy

OrganismSus scrofa [Animal]

FamilyDefensin

Tax ID9823

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence