Peptide Database

Peptide NamePseudhymenochirin-2Pa [E27K]

Function Ontology

Anticancer

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length27 amino acids

Chemical FormulaC136H235N35O32

DescriptionStandard

        GIFPIFAKLLGKVIKVASSLISKGRTK
    

Molecular Weight2872.54 Da

Isoelectric Point (pI)11.39

Net Charge (pH 7.0)5.76

Net Charge (pH 7.4) 5.54

Charge Density (pH 7.0) 0.2132

GRAVY Index0.63

Hydrophobic Moment 0.69

Boman Index0.20

Instability Index1.89

Aliphatic Index 130.00

Aromaticity 0.0741

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1084.05

LogP -7.17

H-bond Donors 39.0

H-bond Acceptors 38.0

Rotatable Bonds 100.0

Heavy Atoms 203.0

Ring Count 3.0

Amide Bonds 26.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0078423 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Other Modsk=D-Lys

Bio-Activity Profile

Function

Antimicrobial Anticancer Hemolytic

TargetMouse erythrocytes: ±1μM

Activity50 %

MethodHemolysis

RECORD: Rec_0127252 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Other Modsk=D-Lys

Bio-Activity Profile

Function

Antimicrobial Anticancer

TargetHT-29

Activity5.6±0.4 μM

MethodIC50

RECORD: Rec_0309938 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Other Modsk=D-Lys

Bio-Activity Profile

Function

Antimicrobial Anticancer Cytotoxic

RECORD: Rec_0332624 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Other Modsk=D-Lys

Bio-Activity Profile

Function

Antimicrobial Anticancer

TargetA549

Activity2.5±0.5 μM

MethodIC50

RECORD: Rec_0335587 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Other Modsk=D-Lys

Bio-Activity Profile

Function

Antimicrobial Anticancer

TargetMDA-MB-231

Activity4.3±0.2 μM

MethodIC50