Peptide Database

Peptide NameAla54 substitution mutant of pAntp (43-58)

Function Ontology

Anticancer

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide

Delivery / Targeting ▸ Drug delivery vehicle

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length16 amino acids

Chemical FormulaC102H164N34O20

DescriptionStandard

        RQIKIWFQNRRAKWKK
    

Molecular Weight2186.61 Da

Isoelectric Point (pI)12.00

Net Charge (pH 7.0)6.76

Net Charge (pH 7.4) 6.55

Charge Density (pH 7.0) 0.4223

GRAVY Index-1.74

Hydrophobic Moment 0.38

Boman Index-0.62

Instability Index46.60

Aliphatic Index 55.00

Aromaticity 0.1875

Extinction Coeff. Reduced 11000.00

Extinction Coeff. Oxidized 11000.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 950.45

LogP -5.81

H-bond Donors 35.0

H-bond Acceptors 27.0

Rotatable Bonds 77.0

Heavy Atoms 156.0

Ring Count 5.0

Amide Bonds 18.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0357947 VERIFIED: YES

Provenance & Taxonomy

OrganismProtein derived [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermBiotinylation (Labeled with Biotinyl-beta-Alanine)

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Anticancer Hemolytic

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